AustralieFrV1, Main, Exploration, bibRecord, 004791

Clinical epidemiology of the global expansion of Klebsiella pneumoniae carbapenemases

Identifieur interne : 004791 ( Main/Exploration ); précédent : 004790; suivant : 004792

Clinical epidemiology of the global expansion of Klebsiella pneumoniae carbapenemases

Auteurs : L Silvia Munoz-Price ; Laurent Poirel ; Robert A. Bonomo ; Mitchell J. Schwaber ; George L. Daikos ; Martin Cormican ; Giuseppe Cornaglia ; Javier Garau ; Marek Gniadkowski ; Mary K. Hayden ; Karthikeyan Kumarasamy ; David M. Livermore ; Juan J. Maya ; Patrice Nordmann ; Jean B. Patel ; David L. Paterson ; Johann Pitout ; Maria Virginia Villegas ; Hui Wang ; Neil Woodford ; John P. Quinn

Source :

The Lancet. Infectious diseases [ 1473-3099 ] ; 2013.

RBID : PMC:4673667

Abstract

Klebsiella pneumoniae carbapenemases (KPCs) were originally identified in the USA in 1996. Since then, these versatile β-lactamases have spread internationally among Gram-negative bacteria, especially K pneumoniae, although their precise epidemiology is diverse across countries and regions. The mortality described among patients infected with organisms positive for KPC is high, perhaps as a result of the limited antibiotic options remaining (often colistin, tigecycline, or aminoglycosides). Triple drug combinations using colistin, tigecycline, and imipenem have recently been associated with improved survival among patients with bacteraemia. In this Review, we summarise the epidemiology of KPCs across continents, and discuss issues around detection, present antibiotic options and those in development, treatment outcome and mortality, and infection control. In view of the limitations of present treatments and the paucity of new drugs in the pipeline, infection control must be our primary defence for now.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673667

DOI: 10.1016/S1473-3099(13)70190-7
PubMed: 23969216
PubMed Central: 4673667

Affiliations:

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Clinical epidemiology of the global expansion of <italic>Klebsiella pneumoniae</italic>
 carbapenemases</title>
<author><name sortKey="Munoz Price, L Silvia" sort="Munoz Price, L Silvia" uniqKey="Munoz Price L" first="L Silvia" last="Munoz-Price">L Silvia Munoz-Price</name>
</author>
<author><name sortKey="Poirel, Laurent" sort="Poirel, Laurent" uniqKey="Poirel L" first="Laurent" last="Poirel">Laurent Poirel</name>
</author>
<author><name sortKey="Bonomo, Robert A" sort="Bonomo, Robert A" uniqKey="Bonomo R" first="Robert A" last="Bonomo">Robert A. Bonomo</name>
</author>
<author><name sortKey="Schwaber, Mitchell J" sort="Schwaber, Mitchell J" uniqKey="Schwaber M" first="Mitchell J" last="Schwaber">Mitchell J. Schwaber</name>
</author>
<author><name sortKey="Daikos, George L" sort="Daikos, George L" uniqKey="Daikos G" first="George L" last="Daikos">George L. Daikos</name>
</author>
<author><name sortKey="Cormican, Martin" sort="Cormican, Martin" uniqKey="Cormican M" first="Martin" last="Cormican">Martin Cormican</name>
</author>
<author><name sortKey="Cornaglia, Giuseppe" sort="Cornaglia, Giuseppe" uniqKey="Cornaglia G" first="Giuseppe" last="Cornaglia">Giuseppe Cornaglia</name>
</author>
<author><name sortKey="Garau, Javier" sort="Garau, Javier" uniqKey="Garau J" first="Javier" last="Garau">Javier Garau</name>
</author>
<author><name sortKey="Gniadkowski, Marek" sort="Gniadkowski, Marek" uniqKey="Gniadkowski M" first="Marek" last="Gniadkowski">Marek Gniadkowski</name>
</author>
<author><name sortKey="Hayden, Mary K" sort="Hayden, Mary K" uniqKey="Hayden M" first="Mary K" last="Hayden">Mary K. Hayden</name>
</author>
<author><name sortKey="Kumarasamy, Karthikeyan" sort="Kumarasamy, Karthikeyan" uniqKey="Kumarasamy K" first="Karthikeyan" last="Kumarasamy">Karthikeyan Kumarasamy</name>
</author>
<author><name sortKey="Livermore, David M" sort="Livermore, David M" uniqKey="Livermore D" first="David M" last="Livermore">David M. Livermore</name>
</author>
<author><name sortKey="Maya, Juan J" sort="Maya, Juan J" uniqKey="Maya J" first="Juan J" last="Maya">Juan J. Maya</name>
</author>
<author><name sortKey="Nordmann, Patrice" sort="Nordmann, Patrice" uniqKey="Nordmann P" first="Patrice" last="Nordmann">Patrice Nordmann</name>
</author>
<author><name sortKey="Patel, Jean B" sort="Patel, Jean B" uniqKey="Patel J" first="Jean B" last="Patel">Jean B. Patel</name>
</author>
<author><name sortKey="Paterson, David L" sort="Paterson, David L" uniqKey="Paterson D" first="David L" last="Paterson">David L. Paterson</name>
</author>
<author><name sortKey="Pitout, Johann" sort="Pitout, Johann" uniqKey="Pitout J" first="Johann" last="Pitout">Johann Pitout</name>
</author>
<author><name sortKey="Villegas, Maria Virginia" sort="Villegas, Maria Virginia" uniqKey="Villegas M" first="Maria Virginia" last="Villegas">Maria Virginia Villegas</name>
</author>
<author><name sortKey="Wang, Hui" sort="Wang, Hui" uniqKey="Wang H" first="Hui" last="Wang">Hui Wang</name>
</author>
<author><name sortKey="Woodford, Neil" sort="Woodford, Neil" uniqKey="Woodford N" first="Neil" last="Woodford">Neil Woodford</name>
</author>
<author><name sortKey="Quinn, John P" sort="Quinn, John P" uniqKey="Quinn J" first="John P" last="Quinn">John P. Quinn</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">23969216</idno>
<idno type="pmc">4673667</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673667</idno>
<idno type="RBID">PMC:4673667</idno>
<idno type="doi">10.1016/S1473-3099(13)70190-7</idno>
<date when="2013">2013</date>
<idno type="wicri:Area/Pmc/Corpus">001E01</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001E01</idno>
<idno type="wicri:Area/Pmc/Curation">001C57</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001C57</idno>
<idno type="wicri:Area/Pmc/Checkpoint">001C09</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">001C09</idno>
<idno type="wicri:Area/Ncbi/Merge">001429</idno>
<idno type="wicri:Area/Ncbi/Curation">001429</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">001429</idno>
<idno type="wicri:doubleKey">1473-3099:2013:Munoz Price L:clinical:epidemiology:of</idno>
<idno type="wicri:Area/Main/Merge">004907</idno>
<idno type="wicri:Area/Main/Curation">004791</idno>
<idno type="wicri:Area/Main/Exploration">004791</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Clinical epidemiology of the global expansion of <italic>Klebsiella pneumoniae</italic>
 carbapenemases</title>
<author><name sortKey="Munoz Price, L Silvia" sort="Munoz Price, L Silvia" uniqKey="Munoz Price L" first="L Silvia" last="Munoz-Price">L Silvia Munoz-Price</name>
</author>
<author><name sortKey="Poirel, Laurent" sort="Poirel, Laurent" uniqKey="Poirel L" first="Laurent" last="Poirel">Laurent Poirel</name>
</author>
<author><name sortKey="Bonomo, Robert A" sort="Bonomo, Robert A" uniqKey="Bonomo R" first="Robert A" last="Bonomo">Robert A. Bonomo</name>
</author>
<author><name sortKey="Schwaber, Mitchell J" sort="Schwaber, Mitchell J" uniqKey="Schwaber M" first="Mitchell J" last="Schwaber">Mitchell J. Schwaber</name>
</author>
<author><name sortKey="Daikos, George L" sort="Daikos, George L" uniqKey="Daikos G" first="George L" last="Daikos">George L. Daikos</name>
</author>
<author><name sortKey="Cormican, Martin" sort="Cormican, Martin" uniqKey="Cormican M" first="Martin" last="Cormican">Martin Cormican</name>
</author>
<author><name sortKey="Cornaglia, Giuseppe" sort="Cornaglia, Giuseppe" uniqKey="Cornaglia G" first="Giuseppe" last="Cornaglia">Giuseppe Cornaglia</name>
</author>
<author><name sortKey="Garau, Javier" sort="Garau, Javier" uniqKey="Garau J" first="Javier" last="Garau">Javier Garau</name>
</author>
<author><name sortKey="Gniadkowski, Marek" sort="Gniadkowski, Marek" uniqKey="Gniadkowski M" first="Marek" last="Gniadkowski">Marek Gniadkowski</name>
</author>
<author><name sortKey="Hayden, Mary K" sort="Hayden, Mary K" uniqKey="Hayden M" first="Mary K" last="Hayden">Mary K. Hayden</name>
</author>
<author><name sortKey="Kumarasamy, Karthikeyan" sort="Kumarasamy, Karthikeyan" uniqKey="Kumarasamy K" first="Karthikeyan" last="Kumarasamy">Karthikeyan Kumarasamy</name>
</author>
<author><name sortKey="Livermore, David M" sort="Livermore, David M" uniqKey="Livermore D" first="David M" last="Livermore">David M. Livermore</name>
</author>
<author><name sortKey="Maya, Juan J" sort="Maya, Juan J" uniqKey="Maya J" first="Juan J" last="Maya">Juan J. Maya</name>
</author>
<author><name sortKey="Nordmann, Patrice" sort="Nordmann, Patrice" uniqKey="Nordmann P" first="Patrice" last="Nordmann">Patrice Nordmann</name>
</author>
<author><name sortKey="Patel, Jean B" sort="Patel, Jean B" uniqKey="Patel J" first="Jean B" last="Patel">Jean B. Patel</name>
</author>
<author><name sortKey="Paterson, David L" sort="Paterson, David L" uniqKey="Paterson D" first="David L" last="Paterson">David L. Paterson</name>
</author>
<author><name sortKey="Pitout, Johann" sort="Pitout, Johann" uniqKey="Pitout J" first="Johann" last="Pitout">Johann Pitout</name>
</author>
<author><name sortKey="Villegas, Maria Virginia" sort="Villegas, Maria Virginia" uniqKey="Villegas M" first="Maria Virginia" last="Villegas">Maria Virginia Villegas</name>
</author>
<author><name sortKey="Wang, Hui" sort="Wang, Hui" uniqKey="Wang H" first="Hui" last="Wang">Hui Wang</name>
</author>
<author><name sortKey="Woodford, Neil" sort="Woodford, Neil" uniqKey="Woodford N" first="Neil" last="Woodford">Neil Woodford</name>
</author>
<author><name sortKey="Quinn, John P" sort="Quinn, John P" uniqKey="Quinn J" first="John P" last="Quinn">John P. Quinn</name>
</author>
</analytic>
<series><title level="j">The Lancet. Infectious diseases</title>
<idno type="ISSN">1473-3099</idno>
<idno type="eISSN">1474-4457</idno>
<imprint><date when="2013">2013</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p id="P1"><italic>Klebsiella pneumoniae</italic>
 carbapenemases (KPCs) were originally identified in the USA in 1996. Since then, these versatile β-lactamases have spread internationally among Gram-negative bacteria, especially <italic>K pneumoniae</italic>
, although their precise epidemiology is diverse across countries and regions. The mortality described among patients infected with organisms positive for KPC is high, perhaps as a result of the limited antibiotic options remaining (often colistin, tigecycline, or aminoglycosides). Triple drug combinations using colistin, tigecycline, and imipenem have recently been associated with improved survival among patients with bacteraemia. In this Review, we summarise the epidemiology of KPCs across continents, and discuss issues around detection, present antibiotic options and those in development, treatment outcome and mortality, and infection control. In view of the limitations of present treatments and the paucity of new drugs in the pipeline, infection control must be our primary defence for now.</p>
</div>
</front>
</TEI>
<affiliations><list></list>
<tree><noCountry><name sortKey="Bonomo, Robert A" sort="Bonomo, Robert A" uniqKey="Bonomo R" first="Robert A" last="Bonomo">Robert A. Bonomo</name>
<name sortKey="Cormican, Martin" sort="Cormican, Martin" uniqKey="Cormican M" first="Martin" last="Cormican">Martin Cormican</name>
<name sortKey="Cornaglia, Giuseppe" sort="Cornaglia, Giuseppe" uniqKey="Cornaglia G" first="Giuseppe" last="Cornaglia">Giuseppe Cornaglia</name>
<name sortKey="Daikos, George L" sort="Daikos, George L" uniqKey="Daikos G" first="George L" last="Daikos">George L. Daikos</name>
<name sortKey="Garau, Javier" sort="Garau, Javier" uniqKey="Garau J" first="Javier" last="Garau">Javier Garau</name>
<name sortKey="Gniadkowski, Marek" sort="Gniadkowski, Marek" uniqKey="Gniadkowski M" first="Marek" last="Gniadkowski">Marek Gniadkowski</name>
<name sortKey="Hayden, Mary K" sort="Hayden, Mary K" uniqKey="Hayden M" first="Mary K" last="Hayden">Mary K. Hayden</name>
<name sortKey="Kumarasamy, Karthikeyan" sort="Kumarasamy, Karthikeyan" uniqKey="Kumarasamy K" first="Karthikeyan" last="Kumarasamy">Karthikeyan Kumarasamy</name>
<name sortKey="Livermore, David M" sort="Livermore, David M" uniqKey="Livermore D" first="David M" last="Livermore">David M. Livermore</name>
<name sortKey="Maya, Juan J" sort="Maya, Juan J" uniqKey="Maya J" first="Juan J" last="Maya">Juan J. Maya</name>
<name sortKey="Munoz Price, L Silvia" sort="Munoz Price, L Silvia" uniqKey="Munoz Price L" first="L Silvia" last="Munoz-Price">L Silvia Munoz-Price</name>
<name sortKey="Nordmann, Patrice" sort="Nordmann, Patrice" uniqKey="Nordmann P" first="Patrice" last="Nordmann">Patrice Nordmann</name>
<name sortKey="Patel, Jean B" sort="Patel, Jean B" uniqKey="Patel J" first="Jean B" last="Patel">Jean B. Patel</name>
<name sortKey="Paterson, David L" sort="Paterson, David L" uniqKey="Paterson D" first="David L" last="Paterson">David L. Paterson</name>
<name sortKey="Pitout, Johann" sort="Pitout, Johann" uniqKey="Pitout J" first="Johann" last="Pitout">Johann Pitout</name>
<name sortKey="Poirel, Laurent" sort="Poirel, Laurent" uniqKey="Poirel L" first="Laurent" last="Poirel">Laurent Poirel</name>
<name sortKey="Quinn, John P" sort="Quinn, John P" uniqKey="Quinn J" first="John P" last="Quinn">John P. Quinn</name>
<name sortKey="Schwaber, Mitchell J" sort="Schwaber, Mitchell J" uniqKey="Schwaber M" first="Mitchell J" last="Schwaber">Mitchell J. Schwaber</name>
<name sortKey="Villegas, Maria Virginia" sort="Villegas, Maria Virginia" uniqKey="Villegas M" first="Maria Virginia" last="Villegas">Maria Virginia Villegas</name>
<name sortKey="Wang, Hui" sort="Wang, Hui" uniqKey="Wang H" first="Hui" last="Wang">Hui Wang</name>
<name sortKey="Woodford, Neil" sort="Woodford, Neil" uniqKey="Woodford N" first="Neil" last="Woodford">Neil Woodford</name>
</noCountry>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 004791 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 004791 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Asie
   |area=    AustralieFrV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     PMC:4673667
   |texte=   Clinical epidemiology of the global expansion of Klebsiella pneumoniae carbapenemases
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:23969216" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a AustralieFrV1

This area was generated with Dilib version V0.6.33.
Data generation: Tue Dec 5 10:43:12 2017. Site generation: Tue Mar 5 14:07:20 2024

Serveur d'exploration sur les relations entre la France et l'Australie

Clinical epidemiology of the global expansion of Klebsiella pneumoniae carbapenemases

Clinical epidemiology of the global expansion of Klebsiella pneumoniae carbapenemases

Source :

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration sur les relations entre la France et l'Australie
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.